tert-Butyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate

tert-Butyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate - Names and Identifiers

Name	1-Amino-6-azaspiro[2.5]octane-6-carboxylic acid tert-butyl ester
Synonyms	1-Amino-6-azaspiro[2.5]octane-6-carboxylic tert-butyl 1-aMino-6-azaspiro[2.5]octane-6-carboxylate Tert-butyl 2-amino-6-azaspiro[2.5]octane-6-carboxylate tert-Butyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate 1-Amino-6-azaspiro[2.5]octane-6-carboxylic acid tert-butyl ester 1-Amino-6-aza-spiro[2.5]octane-6-carboxylic acid tert-butyl ester 6-Azaspiro[2.5]octane-6-carboxylic acid, 1-aMino-,1,1-diMethylethyl ester 6-Azaspiro[2.5]octane-6-carboxylic acid, 1-amino-,1,1-dimethylethyl ester
CAS	1233323-55-1

tert-Butyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate - Physico-chemical Properties

Molecular Formula	C12H22N2O2
Molar Mass	226.32
Density	1.10
Boling Point	319℃
Flash Point	147℃
pKa	9.03±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

tert-Butyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate - Introduction

tert-butyl l-amino-6-azaspiro [2.5] octane-6-carboxylate, also known as TBDACS, is an organic compound. The following is a description of the nature, use, preparation and safety information of TBDACS:

Nature:
-Appearance: TBDACS is a colorless to light yellow liquid.
-Solubility: TBDACS has good solubility in non-polar solvents.
-Melting point and boiling point: The melting point and boiling point of the compound will vary with the specific chemical structure.

Use:
TBDACS has many uses in organic synthesis, including the following:
-Chemical catalyst: TBDACS can be used as a precursor of the catalyst or the catalyst itself, used for acidic or basic catalysis in organic reactions.
-Polymer materials: TBDACS can be used as a crosslinking agent for synthetic polymers or copolymers to prepare polymer materials with specific properties or applications.
-Drug intermediates: TBDACS can be used as an intermediate for the synthesis of certain drugs, used to prepare the structural or functional units of drug molecules.

Preparation Method:
The preparation method of TBDACS can use different synthetic routes according to specific needs. The following is a common preparation method:
1. Mix an appropriate amount of 6-azaspiro [2.5] octane -6-carboxylic acid and an appropriate amount of alcohol (such as tert-butyl alcohol) in an appropriate solvent.
2. under the appropriate temperature and reaction time, add a certain amount of ammonia gas.
3. the esterification reaction under common reaction conditions.
4. After the reaction is completed, the target compound is obtained by an appropriate separation and purification process.

Safety Information:
TBDACS is an organic compound and requires appropriate safety measures in operation:
-Use personal protective equipment such as protective gloves and safety glasses.
-Operate in a well-ventilated laboratory to avoid inhalation of its vapors or skin contact.
-Compliance with storage and handling regulations for chemicals.
-Evaluate the toxicity and harmfulness of compounds on a case-by-case basis, in compliance with relevant regulations and standards.

Last Update：2024-04-10 22:41:03